Hypoxia stabilizes SETDB1 to maintain genome stability

Park, S; Cho, JH; Kim, JH; Park, M; Park, S; Kim, SY; Kim, SK; Kim, K; Park, SG; Park, BC; Moon, JH; Lee, G; Kim, S; Kim, JA; Kim, JH

Kim, JA; Kim, JH (通讯作者),Korea Res Inst Biosci & Biotechnol, Dis Target Struct Res Ctr, Daejeon 34141, South Korea.;Kim, JA (通讯作者),Korea Res Inst Biosci & Biotechnol, Aging Convergence Res Ctr, Daejeon 34141, South Korea.;Kim, JA; Kim, JH (通讯作者),Univ Sci & Technol, Dept Biosci, Daejeon 34113, South Korea.;Kim, JH (通讯作者),Chungnam Natl Univ, Grad Sch New Drug Discovery & Dev, Daejeon 34134, South Korea.

NUCLEIC ACIDS RESEARCH, 2023; 51 (20): 11178

Abstract

Von Hippel-Lindau (VHL) is a tumor suppressor that functions as the substrate recognition subunit of the CRL2(VHL) E3 complex. While substrates of VHL......

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