Multiomics analysis of the NAD(+)-PARP1 axis reveals a role for site-specific ADP-ribosylation in splicing in embryonic stem cells

Jones, A; Kraus, WL

Kraus, WL (通讯作者)，Univ Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Express, Dallas, TX 75390 USA.;Kraus, WL (通讯作者)，Univ Texas Southwestern Med Ctr, Dept Obstet andGynecol, Div Basic Res, Dallas, TX 75390 USA.;Kraus, WL (通讯作者)，Univ Texas Southwestern Med Ctr, Grad Sch Biomed Sci, Program Genet Dev & Dis, Dallas, TX 75390 USA.

GENES & DEVELOPMENT, 2022; 36 (9-10): 601

Abstract

The differentiation of embryonic stem cells (ESCs) into a lineage-committed state is a dynamic process involving changes in cellular metabolism, epige......

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