Detection of Alzheimer's disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein

Ji, B; Ono, M; Yamasaki, T; Fujinaga, M; Zhang, MR; Seki, C; Aoki, I; Kito, S; Sawada, M; Suhara, T; Sahara, N; Higuchi, M

Ji, B (corresponding author), Natl Inst Quantum & Radiol Sci & Technol, Natl Inst Radiol Sci, Inage Ku, 4-9-1 Anagawa, Chiba 2638555, Japan.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2021; 41 (8): 2076

Abstract

A substantial and constitutive expression of translocator protein (TSPO) in cerebral blood vessels hampers the sensitive detection of neuroinflammatio......

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