Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease

Bao, WD; Pang, P; Zhou, XT; Hu, F; Xiong, W; Chen, K; Wang, J; Wang, FD; Xie, D; Hu, YZ; Han, ZT; Zhang, HH; Wang, WX; Nelson, PT; Chen, JG; Lu, YM; Man, HY; Liu, D; Zhu, LQ

Zhu, LQ (corresponding author), Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Basic Med, Dept Pathophysiol,Key Lab Neurol Disorder,Educ Mi, Wuhan 430030, Peoples R China.; Zhu, LQ (corresponding author), Huazhong Univ Sci & Technol, Collaborat Innovat Ctr Brain Sci, Inst Brain Res, Wuhan 430030, Peoples R China.

CELL DEATH AND DIFFERENTIATION, ; ():

Abstract

Iron homeostasis disturbance has been implicated in Alzheimer's disease (AD), and excess iron exacerbates oxidative damage and cognitive defects. Ferr......

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