Efficacy of Selpercatinib in RET-Altered Thyroid Cancers

Wirth, LJ; Sherman, E; Robinson, B; Solomon, B; Kang, H; Lorch, J; Worden, F; Brose, M; Patel, J; Leboulleux, S; Godbert, Y; Barlesi, F; Morris, JC; Owonikoko, TK; Tan, DSW; Gautschi, O; Weiss, J; de la Fouchardiere, C; Burkard, ME; Laskin, J; Taylor, MH; Kroiss, M; Medioni, J; Goldman, JW; Bauer, TM; Levy, B; Zhu, VW; Lakhani, N; Moreno, V; Ebata, K; Nguyen, M; Heirich, D; Zhu, EY; Huang, X; Yang, L; Kherani, J; Rothenberg, SM; Drilon, A; Subbiah, V; Shah, MH; Cabanillas, ME

Wirth, LJ (corresponding author), Massachusetts Gen Hosp, 55 Fruit St, Boston, MA 02114 USA.

NEW ENGLAND JOURNAL OF MEDICINE, 2020; 383 (9): 825

Abstract

BACKGROUND RET mutations occur in 70% of medullary thyroid cancers, and RET fusions occur rarely in other thyroid cancers. In patients with RET-altere......

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