Investigating the Mechanism of Trimethoprim-Induced Skin Rash and Liver Injury

Cao, YS; Bairam, A; Jee, A; Liu, M; Uetrecht, J

Uetrecht, J (corresponding author), Univ Toronto, Fac Pharm, 144 Coll St, Toronto, ON M5S 3M2, Canada.

TOXICOLOGICAL SCIENCES, 2021; 180 (1): 17

Abstract

Trimethoprim (TMP)-induced skin rash and liver injury are likely to involve the formation of reactive metabolites. Analogous to nevirapine-induced ski......

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