The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum

Larsen, HA; Atkins, WM; Nath, A

Nath, A (通讯作者),Univ Washington, Dept Med Chem, Box 357610, Seattle, WA 98195 USA.

PROTEIN SCIENCE, 2023; 32 (12):

Abstract

The development of therapeutic antibodies remains challenging, time-consuming, and expensive. A key contributing factor is a lack of understanding of ......

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