Identification of Sca-1(+)Abcg1(+) bronchioalveolar epithelial cells as the origin of lung adenocarcinoma in Gprc5a-knockout mouse model through the interaction between lung progenitor AT2 and Lgr5 cells

Yin, HJ; Jiang, ZY; Feng, X; Ji, ZD; Jin, W

Yin, HJ (corresponding author), Fudan Univ, Inst Canc, Shanghai Canc Ctr, Shanghai 200032, Peoples R China.; Yin, HJ (corresponding author), Fudan Univ, Shanghai Med Sch, Dept Oncol, Shanghai 200032, Peoples R China.

ONCOGENE, 2020; 39 (18): 3754

Abstract

The reason for the reduced efficacy of lung cancer therapy is the existence of lung cancer stem cells (CSCs). Targeting CSCs results in evolved phenot......

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