Glycoproteomics of a Single Protein: Revealing Tens of Thousands of Myozyme Glycoforms by Hybrid HPLC-MS Approaches

Di Marco, F; Blöchl, C; Esser-Skala, W; Schäpertöns, V; Zhang, T; Wuhrer, M; Sandra, K; Wohlschlager, T; Huber, CG

Huber, CG (通讯作者),Univ Salzburg, Dept Biosci & Med Biol, Bioanalyt Res Labs, Salzburg, Austria.;Huber, CG (通讯作者),Univ Salzburg, Christian Doppler Lab Innovat Tools Biosimilar Cha, Salzburg, Austria.

MOLECULAR & CELLULAR PROTEOMICS, 2023; 22 (9):

Abstract

Characterization of highly glycosylated biopharmaceuticals by mass spectrometry is challenging because of the huge chemical space of coexistent glycof......

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