IFN-gamma-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1 alpha

Van Dis, E; Fox, DM; Morrison, HM; Fines, DM; Babirye, JP; McCann, LH; Rawal, S; Cox, JS; Stanley, SA

Stanley, SA (通讯作者)，Univ Calif Berkeley, Dept Mol & Cell Biol, Div Immunol & Pathogenesis, Berkeley, CA 94720 USA.;Stanley, SA (通讯作者)，Univ Calif Berkeley, Sch Publ Hlth, Div Infect Dis & Vaccinol, Berkeley, CA 94704 USA.

PLOS PATHOGENS, 2022; 18 (7):

Abstract

The prevailing model of protective immunity to tuberculosis is that CD4 T cells produce the cytokine IFN-gamma to activate bactericidal mechanisms in ......

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