GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice

Yamamoto, H; Lee-Okada, HC; Ikeda, M; Nakamura, T; Saito, T; Takata, A; Yokomizo, T; Iwata, N; Kato, T; Kasahara, T

Kato, T; Kasahara, T (通讯作者)，RIKEN, Ctr Brain Sci, Lab Mol Dynam Mental Disorders, Saitama, Japan.;Kato, T (通讯作者)，Juntendo Univ, Grad Sch Med, Dept Psychiat & Behav Sci, Tokyo, Japan.;Kasahara, T (通讯作者)，RIKEN, Ctr Brain Sci, Career Dev Program, Saitama, Japan.;Kasahara, T (通讯作者)，RIKEN, Ctr Brain Sci, Neurodegenerat Disorders Collaborat Lab, Saitama, Japan.;Kasahara, T (通讯作者)，Carl von Ossietzky Univ Oldenburg, Inst Biol & Environm Sci, Oldenburg, Germany.

MOLECULAR PSYCHIATRY, 2023; 28 (7): 2848

Abstract

Large-scale genome-wide association studies (GWASs) on bipolar disorder (BD) have implicated the involvement of the fatty acid desaturase (FADS) locus......

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