Single protein encapsulated SN38 for tumor-targeting treatment

Yu, CJ; Huang, FQ; Wang, KS; Liu, MM; Chow, WA; Ling, X; Li, FZ; Causey, JL; Huang, XZ; Cook-Wiens, G; Cui, XJ

Yu, CJ (通讯作者)，CALTECH, Dept Chem, Pasadena, CA 91125 USA.;Yu, CJ (通讯作者)，Sunstate Biosci LLC, 870 S Myrtle Ave, Monrovia, CA 91016 USA.;Huang, FQ (通讯作者)，Univ Southern Mississippi, Dept Chem & Biochem, Hattiesburg, MS 39406 USA.;Cui, XJ (通讯作者)，Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Dept Surg, Los Angeles, CA 90048 USA.

JOURNAL OF TRANSLATIONAL MEDICINE, 2023; 21 (1):

Abstract

BackgroundThe alkaloid camptothecin analog SN38 is a potent antineoplastic agent, but cannot be used directly for clinical application due to its poor......

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