Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017-2019

Ruger, J; Ioannou, S; Castanotto, D; Stein, CA

Castanotto, D; Stein, CA (corresponding author), City Hope Natl Med Ctr, Irell & Manella Grad Sch Biol Sci, 1500 East Duarte Rd, Duarte, CA 91010 USA.; Castanotto, D; Stein, CA (corresponding author), City Hope Natl Med Ctr, Dept Med Oncol, 1500 East Duarte Rd, Duarte, CA 91010 USA.; Stein, CA (corresponding author), City Hope Natl Med Ctr, Dept Mol & Cellular Biol, 1500 East Duarte Rd, Duarte, CA 91010 USA.

TRENDS IN PHARMACOLOGICAL SCIENCES, 2020; 41 (1): 27

Abstract

Four decades have passed since oligonucleotides were first used to manipulate gene expression. There were few FDA approvals prior to 2016, mostly of d......

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