Developing methods to study conformational changes in RNA crystals using a photocaged ligand

Lee, HK; Conrad, CE; Magidson, V; Heinz, WF; Pauly, G; Yu, P; Ramakrishnan, S; Stagno, JR; Wang, YX

Stagno, JR; Wang, YX (通讯作者),NCI, Ctr Struct Biol, Ctr Canc Res, Prot Nucl Acid Interact Sect, Frederick, MD 21702 USA.

FRONTIERS IN MOLECULAR BIOSCIENCES, 2022; 9 ():

Abstract

Crystallographic observation of structural changes in real time requires that those changes be uniform both spatially and temporally. A primary challe......

Full Text Link