Novel H2S-Releasing Bifunctional Antihistamine Molecules with Improved Antipruritic and Reduced Sedative Actions

Antoniadou, I; Georgiou, M; Dotsikas, Y; Lamprou, A; Lougiakis, N; Pouli, N; Karousis, N; Loukas, Y; Tseti, I; Marakos, P; Papapetropoulos, A

Papapetropoulos, A (通讯作者)，Biomed Res Fdn Acad Athens, 4 Soranou Efesiou Str, Athens 11527, Greece.;Marakos, P (通讯作者)，Natl & Kapodistrian Univ Athens, Dept Pharm, Div Pharmaceut Chem, Panepistimiopolis Zografou, Athens 15771, Greece.;Papapetropoulos, A (通讯作者)，Natl & Kapodistrian Univ Athens, Athens 15771, Greece.

JOURNAL OF MEDICINAL CHEMISTRY, 2023; 66 (14): 9607

Abstract

Hydrogen sulfide (H2S) is an endogenous gasotransmitterwith anti-inflammatory actions that also reduces itching. To testwhether a combination of an an......

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