Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer

De Nicola, F; Goeman, F; Pallocca, M; Sperati, F; Pizzuti, L; Melucci, E; Casini, B; Amoreo, CA; Gallo, E; Diodoro, MG; Buglioni, S; Mazzotta, M; Vici, P; Sergi, D; Di Lauro, L; Barba, M; Pescarmona, E; Ciliberto, G; De Maria, R; Fanciulli, M; Mauger

Maugeri-Sacca, M (reprint author), IRCCS Regina Elena Natl Canc Inst, Div Med Oncol 2, Via Elio Chianesi 53, I-00144 Rome, Italy.; De Maria, R (reprint author), Univ Cattolica Sacro Cuore, Inst Gen Pathol, Largo Agostino Gemelli 10, I-00168 Rome, Italy.

ONCOGENESIS, 2018; 7 ():

Abstract

Genomic technologies are reshaping the molecular landscape of colorectal cancer (CRC), revealing that oncogenic driver mutations (APC and TP53) coexis......

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