PTEN-Induced Putative Kinase 1 (PINK1)/Parkin-Mediated Mitophagy Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity

Zhang, Y; Liu, QZ; Li, YL; Li, CJ; Zhu, YH; Xia, F; Xu, SQ; Li, WY

Xu, SQ (reprint author), Nanjing Med Univ, Nanjing Matern & Child Hlth Care Hosp, Dept Anesthesiol, Womens Hosp, Nanjing, Jiangsu, Peoples R China.; Li, WY (reprint author), Nanjing Med Univ, Dept Anesthesiol, Affiliated Jinling Hosp, Nanjing, Jiangsu, Pe

MEDICAL SCIENCE MONITOR, 2019; 25 (): 8797

Abstract

Background: The pathogenesis of chemotherapy-induced neuropathy, a dose-dependent adverse effect of cisplatin, involves mitochondrial dysfunction. PTE......

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