An engineered prime editor with enhanced editing efficiency in plants

Zong, Y; Liu, YJ; Xue, CX; Li, BS; Li, XY; Wang, YP; Li, J; Liu, GW; Huang, XX; Cao, XF; Gao, CX

Gao, CX (通讯作者)，Chinese Acad Sci, Innovat Acad Seed Design, State Key Lab Plant Cell & Chromosome Engn, Ctr Genome Editing,Inst Genet & Dev Biol, Beijing, Peoples R China.;Cao, XF; Gao, CX (通讯作者)，Univ Chinese Acad Sci, Coll Adv Agr Sci, Beijing, Peoples R China.;Cao, XF (通讯作者)，Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing, Peoples R China.;Cao, XF (通讯作者)，Chinese Acad Sci, Ctr Excellence Mol Plant Sci, Beijing, Peoples R China.

NATURE BIOTECHNOLOGY, 2022; 40 (9): 1394

Abstract

Prime editing is a versatile genome-editing technology, but it suffers from low editing efficiency. In the present study, we introduce optimized prime......

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