Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease

Gola, D; Erdmann, J; Lall, K; Magi, R; Muller-Myhsok, B; Schunkert, H; Konig, IR

Konig, IR (corresponding author), Univ Lubeck, Inst Med Biometrie & Stat, Ratzeburger Allee 160, D-23562 Lubeck, Germany.

CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2020; 13 (6): 569

Abstract

Background: Individual risk prediction based on genome-wide polygenic risk scores (PRSs) using millions of genetic variants has attracted much attenti......

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