Case report of three EGFR TKI naive lung adenocarcinoma containing double EGFR mutations (L858R/T790M or Exon 19 Deletion/T790M); Comparing genetic information and histology

Sakashita, S; Shiba-Ishii, A; Murata, Y; Sekimoto, R; Minami, Y; Sato, Y; Noguchi, M

Sakashita, S (reprint author), Univ Tsukuba, Fac Med, Dept Pathol, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058575, Japan.

PATHOLOGY RESEARCH AND PRACTICE, 2018; 214 (8): 1224

Abstract

EGFR T790M mutation is a crucial gene alteration causing EGFR TKI resistance. However, the implication of T790M mutation is still unknown for the step......

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