Acquired resistance to BRAF inhibition in RAF(V600E) mutant gliomas

Yao, TW; Zhang, J; Prados, M; Weiss, WA; James, CD; Nicolaides, T

Yao, TW; Nicolaides, T (reprint author), Univ Calif San Francisco, Dept Pediat, San Francisco, CA 94143 USA.; Nicolaides, T (reprint author), Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA.

ONCOTARGET, 2017; 8 (1): 583

Abstract

Activating mutation of BRAF is a common finding in pediatric gliomas. As many as 14% of high grade and up to 66% of certain subtypes of low grade pedi......

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