Mutasynthesis of Antibacterial Halogenated Actinomycin Analogues

Yao, ZW; Sun, CL; Xia, YH; Wang, F; Fu, LW; Ma, JY; Li, QL; Ju, JH

Ju, JH (corresponding author), Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, RNAM Ctr Marine Microbiol,Guangdong Key Lab Marin, Guangzhou 510301, Peoples R China.; Ju, JH (corresponding author), Univ Chinese Acad Sci, Coll Oceanol, Beijing 100049, Peoples R China.; Ju, JH (corresponding author), Southern Marine Sci & Engn Guangdong Lab Guangzho, Guangzhou 510301, Peoples R China.

JOURNAL OF NATURAL PRODUCTS, 2021; 84 (8): 2217

Abstract

Through precursor-directed biosynthesis, feeding halogenated (F-, Cl-, Br-, I-) or methoxy-substituted 4-methyl-3-hydroxyanthranilic acid (4-MHA) anal......

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