Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells

de Almeida, LC; Bauermeister, A; Rezende-Teixeira, P; dos Santos, EA; de Moraes, LAB; Machado-Neto, JA; Costa-Lotufo, LV

Costa-Lotufo, LV (reprint author), Univ Sao Paulo, Inst Biomed Sci, Dept Pharmacol, Av Prof Lineu Prestes 1524, BR-05508900 Sao Paulo, SP, Brazil.

BIOCHEMICAL PHARMACOLOGY, 2019; 168 (): 38

Abstract

DNA-damaging agents are widely used in cancer therapy; however, their use is limited by dose-related toxicities, as well as the development of drug re......

Full Text Link