Generation of bispecific antibodies by structure-guided redesign of IgG constant regions

Iwasaki, YW; Tharakaraman, K; Subramanian, V; Hatas, A; Fleischer, E; Rurak, TT; Ngok-ngam, P; Tit-oon, P; Ruchirawat, M; Khongmanee, A; Satayavivad, J; Fuangthong, M; Sasisekharan, R

Sasisekharan, R (通讯作者)，MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA.;Fuangthong, M (通讯作者)，Chulabhorn Res Inst, Translat Res Unit, Bangkok, Thailand.;Fuangthong, M (通讯作者)，Minist Higher Educ Sci Res & Innovat, Ctr Excellence Environm Hlth & Toxicol EHT, Off Permanent Secretary OPS, Bangkok, Thailand.;Fuangthong, M (通讯作者)，Chulabhorn Grad Inst, Program Appl Biol Sci, Bangkok, Thailand.;Sasisekharan, R (通讯作者)，MIT, Dept Biol Engn, Cambridge, MA 02139 USA.

FRONTIERS IN IMMUNOLOGY, 2023; 13 ():

Abstract

Bispecific antibodies (BsAbs) form an exciting class of bio-therapeutics owing to their multispecificity. Although numerous formats have been develope......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索