Structural insight into the macrocyclic inhibitor TPX-0022 of c-Met and c-Src

Qu, LZ; Lin, H; Dai, SY; Guo, M; Chen, XJ; Jiang, LY; Zhang, HJ; Li, MY; Liang, XJ; Chen, ZC; Wei, HD; Chen, YH

Wei, HD; Chen, YH (通讯作者)，Cent South Univ, Xiangya Hosp, Dept Oncol,State Local Joint Engn Lab Anticanc Dru, NHC Key Lab Canc Prote, Changsha 410008, Hunan, Peoples R China.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2023; 21 (): 5712

Abstract

c-Met has been an attractive target of prognostic and therapeutic studies in various cancers. TPX-0022 is a macrocyclic inhibitor of c-Met, c-Src and ......

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