Effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of gliclazide in healthy subjects

Kang, P; Cho, CK; Jang, CG; Lee, SY; Lee, YJ; Choi, CI; Bae, JW

Lee, SY (通讯作者)，Sungkyunkwan Univ, Sch Pharm, Suwon 16419, South Korea.;Choi, CI (通讯作者)，Dongguk Univ Seoul, Coll Pharm, Goyang 10326, South Korea.;Bae, JW (通讯作者)，Keimyung Univ, Coll Pharm, Daegu 42601, South Korea.

ARCHIVES OF PHARMACAL RESEARCH, 2023; 46 (5): 438

Abstract

Gliclazide metabolism is mediated by genetically polymorphic CYP2C9 and CYP2C19 enzymes. We investigated the effects of CYP2C9 and CYP2C19 genetic pol......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索