Simultaneous detection of 5-fluorocytosine and 5-fluorouracil in human cells carrying CD/5-FC suicide gene system by using capillary zone electrophoresis

Liu, YJ; Zhu, P; Huang, ZW; Zhou, L; Shi, P

Shi, P (reprint author), East China Univ Sci & Technol, State Key Lab Bioreactor Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China.; Huang, ZW (reprint author), Donghua Univ, Coll Chem Chem Engn & Biotechnol, 2999 Renmin Rd, Shanghai 201620, Peoples

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018; 1076 (): 1

Abstract

A well-known suicide gene therapy approach, cytosine deaminase (CD) in combination with prodrug 5-flurcytosine (5-FC), has become an effective strateg......

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