Association of Hippocampal Atrophy With Duration of Untreated Psychosis and Molecular Biomarkers During Initial Antipsychotic Treatment of First-Episode Psychosis

Goff, DC; Zeng, BT; Ardekani, BA; Diminich, ED; Tang, YY; Fan, XD; Galatzer-Levy, I; Li, CX; Troxel, AB; Wang, JJ

Goff, DC (reprint author), NYU, Dept Psychiat, Langone Med Ctr, One Pk Ave,Room 8-212, New York, NY 10116 USA.; Wang, JJ (reprint author), Shanghai Jiao Tong Univ, Shanghai Key Lab Psychot Disorders, Shanghai Mental Hlth Ctr, Sch Med, 600 Wanping Nan Rd,

JAMA PSYCHIATRY, 2018; 75 (4): 370

Abstract

IMPORTANCE Duration of untreated psychosis (DUP) has been associated with poor outcomes in schizophrenia, but the mechanism responsible for this assoc......

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