Host SAMHD1 protein restricts endogenous reverse transcription of HIV-1 in nondividing macrophages

Mahboubi, B; Gavegnano, C; Kim, DH; Schinazi, RF; Kim, B

Kim, B (reprint author), Emory Univ, Sch Med, Dept Pediat, Ctr Drug Discovery, Atlanta, GA 30322 USA.

RETROVIROLOGY, 2018; 15 ():

Abstract

BackgroundSAM domain and HD domain containing protein 1 (SAMHD1) is a host anti-HIV-1 restriction factor known to suppress viral reverse transcription......

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