Mismatch repair deficiency, next-generation sequencing-based microsatellite instability, and tumor mutational burden as predictive biomarkers for immune checkpoint inhibitor effectiveness in frontline treatment of advanced stage endometrial cancer-MedSci.cn

Mismatch repair deficiency, next-generation sequencing-based microsatellite instability, and tumor mutational burden as predictive biomarkers for immune checkpoint inhibitor effectiveness in frontline treatment of advanced stage endometrial cancer

Hill, BL; Graf, RP; Shah, KA; Danziger, N; Lin, DI; Quintanilha, J; Li, GR; Haberberger, J; Ross, JS; Santin, AD; Slomovitz, B; Elvin, JA; Ramez, E

Hill, BL (通讯作者)，Univ Calif San Diego, Dept Obstet Gynecol & Reprod Sci, Div Gynecol Oncol, Moores Canc Ctr, La Jolla, CA 92093 USA.

Abstract

ObjectiveMolecular profiling is developing to inform treatment in endometrial cancer. Using real world evidence, we sought to evaluate frontline immun......

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Mismatch repair deficiency, next-generation sequencing-based microsatellite instability, and tumor mutational burden as predictive biomarkers for immune checkpoint inhibitor effectiveness in frontline treatment of advanced stage endometrial cancer

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