A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5

Zhang, YY; Huang, K; Zhang, YX; Han, T; Li, L; Ruan, CC; Sun, YH; Shi, WK; Han, W; Wu, SQ; Song, J; Liu, J; Han, JH

Han, JH (corresponding author), Xiamen Univ, Sch Life Sci, Innovat Ctr Cell Biol, State Key Lab Cellular Stress Biol, Xiamen, Fujian, Peoples R China.; Han, JH (corresponding author), Xiamen Univ, Lab Anim Ctr, Xiamen, Fujian, Peoples R China.; Han, JH (corresponding author), Xiamen Univ, Res Unit Cellular Stress CAMS, Canc Res Ctr, Xiangan Hosp,Sch Med, Xiamen, Fujian, Peoples R China.

PLOS BIOLOGY, 2021; 19 (8):

Abstract

Tumor necrosis factor receptor-1 (TNFR1) signaling, apart from its pleiotropic functions in inflammation, plays a role in embryogenesis as deficiency ......

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