Bioconjugation via Hetero-Selective Clamping of Two Different Amines with ortho-Phthalaldehyde

Chu, X; Li, B; Liu, HY; Sun, XW; Yang, XC; He, G; Zhou, CZ; Xuan, WM; Liu, SL; Chen, G

Chen, G (通讯作者),Nankai Univ, Coll Chem, State Key Lab Elemento Organ Chem, Tianjin 300071, Peoples R China.;Liu, SL (通讯作者),Nankai Univ, Coll Chem, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China.;Liu, SL; Chen, G (通讯作者),Nankai Univ, Frontiers Sci Ctr New Organ Matter, Tianjin 300071, Peoples R China.;Chen, G (通讯作者),Haihe Lab Sustainable Chem Transformat, Tianjin 300192, Peoples R China.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023; 62 (2):

Abstract

Amino groups are common in both natural and synthetic compounds and offer a very attractive class of endogenous handles for bioconjugation. However, t......

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