Chemopreventive efficacy of curcumin-loaded PLGA microparticles in a transgenic mouse model of HER-2-positive breast cancer

Grill, AE; Shahani, K; Koniar, B; Panyam, J

Panyam, J (reprint author), Univ Minnesota, Dept Pharmaceut, Coll Pharm, 9-177 Weaver Densford Hall,308 Harvard St SE, Minneapolis, MN 55455 USA.; Panyam, J (reprint author), Univ Minnesota, Masonic Canc Res Ctr, Minneapolis, MN 55455 USA.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2018; 8 (2): 329

Abstract

Curcumin has shown promising inhibitory activity against HER-2-positive tumor cells in vitro but suffers from poor oral bioavailability in vivo. Our l......

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