Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion

Wei, YY; Ma, Y; Yao, SY; Kong, LH; Liu, X; Chai, JR; Chen, J; Li, W; Wang, YJ; Shao, LM; Liu, JG

Liu, JG (通讯作者)，China Pharmaceut Univ, Sch Basic Med & Clin Pharm, Nanjing 210009, Peoples R China.;Wang, YJ; Liu, JG (通讯作者)，Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China.;Liu, JG (通讯作者)，Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Peoples R China.;Li, W; Shao, LM (通讯作者)，Fudan Univ, Sch Pharm, Dept Med Chem, Shanghai 201203, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2022; 43 (6): 1372

Abstract

SLL-039 (N-cyclopropylmethyl-7 alpha-4'-(N'-benzoyl) amino-phenyl-6,14-endoethano-tetrahydronorthebaine) and SLL-1206 (N-cyclopropylmethyl-7 alpha-3'-......

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