Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance

Flores, A; Argetsinger, LS; Stadler, LKJ; Malaga, AE; Vander, PB; DeSantis, LC; Joe, RM; Cline, JM; Keogh, JM; Henning, E; Barroso, I; de Oliveira, EM; Chandrashekar, G; Clutter, ES; Hu, YX; Stuckey, J; Farooqi, IS; Myers, MG; Carter-Su, C

Carter-Su, C (reprint author), Univ Michigan, Cell & Mol Biol Grad Program, Ann Arbor, MI 48109 USA.; Carter-Su, C (reprint author), Univ Michigan, Dept Mol & Integrat Physiol, Ann Arbor, MI 48109 USA.; Carter-Su, C (reprint author), Univ Michigan, Dept I

DIABETES, 2019; 68 (11): 2049

Abstract

Disruption of the adaptor protein SH2B1 (SH2-B, PSM) is associated with severe obesity, insulin resistance, and neurobehavioral abnormalities in mice ......

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