Blocking K-Ras Interaction With the Plasma Membrane Is a Tractable Therapeutic Approach to Inhibit Oncogenic K-Ras Activity

Henkels, KM; Rehl, KM; Cho, KJ

Cho, KJ (corresponding author), Wright State Univ, Dept Biochem & Mol Biol, Sch Boonshoft Sch Med, Dayton, OH 45435 USA.

FRONTIERS IN MOLECULAR BIOSCIENCES, 2021; 8 ():

Abstract

Ras proteins are membrane-bound small GTPases that promote cell proliferation, differentiation, and apoptosis. Consistent with this key regulatory rol......

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