PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging

Huna, A; Griveau, A; Vindrieux, D; Jaber, S; Flaman, JM; Goehrig, D; Azzi, L; Medard, JJ; Djebali, S; Hernandez-Vargas, H; Dante, R; Payen, L; Marvel, J; Bertolino, P; Aubert, S; Dubus, P; Bernard, D

Bernard, D (corresponding author), Univ Lyon, Ctr Rech Cancerol Lyon, Ctr Leon Berard, Inserm U1052,CNRS UMR 5286, Lyon, France.

CELL DEATH & DISEASE, 2021; 12 (2):

Abstract

Although aging is a major risk factor for most types of cancers, it is barely studied in this context. The transmembrane protein PLA2R1 (phospholipase......

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