The ADP/ATP translocase drives mitophagy independent of nucleotide exchange

Hoshino, A; Wang, WJ; Wada, S; McDermott-Roe, C; Evans, CS; Gosis, B; Morley, MP; Rathi, KS; Li, J; Li, K; Yang, S; McManus, MJ; Bowman, C; Potluri, P; Levin, M; Damrauer, S; Wallace, DC; Holzbaur, ELF; Arany, Z

Arany, Z (reprint author), Univ Penn, Dept Med, Perelman Sch Med, Cardiovasc Inst, Philadelphia, PA 19104 USA.

NATURE, 2019; 575 (7782): 375

Abstract

Mitochondrial homeostasis depends on mitophagy, the programmed degradation of mitochondria. Only a few proteins are known to participate in mitophagy.......

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