Mutant SF3B1 promotes malignancy in PDAC-MedSci.cn

Mutant SF3B1 promotes malignancy in PDAC

Simmler, P; Ioannidi, EI; Mengis, T; Marquart, KF; Asawa, S; Van-Lehmann, K; Kahles, A; Thomas, T; Schwerdel, C; Aceto, N; Rätsch, G; Stoffel, M; Schwank, G

Schwank, G (通讯作者)，Univ Zurich, Inst Pharmacol & Toxicol, Zurich, Switzerland.

ELIFE, 2023; 12 ():

Abstract

The splicing factor SF3B1 is recurrently mutated in various tumors, including pancreatic ductal adenocarcinoma (PDAC). The impact of the hotspot mutat......

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