ChemEM: Flexible Docking of Small Molecules in Cryo-EM Structures

Sweeney, A; Mulvaney, T; Maiorca, M; Topf, M

Topf, M (通讯作者),Leibniz Inst Virol LIV, D-20251 Hamburg, Germany.;Topf, M (通讯作者),Ctr Struct Syst Biol, D-22607 Hamburg, Germany.;Topf, M (通讯作者),Univ Klinikum Hamburg Eppendorf UKE, D-20246 Hamburg, Germany.

JOURNAL OF MEDICINAL CHEMISTRY, 2023; 67 (1): 199

Abstract

Cryo-electron microscopy (cryo-EM), through resolution advancements, has become pivotal in structure-based drug discovery. However, most cryo-EM struc......

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