TPNA10168, an Nrf-2 activator, attenuates inflammatory responses independently of Nrf2 in microglial BV-2 cells: Involvement of the extracellular-signal-regulated kinase pathway

Izumi, Y; Tatsumoto, A; Horiuchi, N; Arifuku, M; Uegomori, M; Kume, T; Koyama, Y

Izumi, Y (通讯作者),Kobe Pharmaceut Univ, Dept Pharmacol, Higashinada Ku, 4-19-1 Motoyamakita Machi, Kobe, Hyogo 6588558, Japan.

JOURNAL OF PHARMACOLOGICAL SCIENCES, 2022; 149 (1): 1

Abstract

Some chemical Nrf2 inducers possess antioxidant and anti-inflammatory properties. TPNA10168, which was identified from a chemical library as a potenti......

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