Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice

Skeltved, N; Nordmaj, MA; Berendtsen, NT; Dagil, R; Stormer, EMR; Al-Nakouzi, N; Jiang, K; Aicher, A; Heeschen, C; Gustavsson, T; Choudhary, S; Gogenur, I; Christensen, JP; Theander, TG; Daugaard, M; Salanti, A; Nielsen, MA

Salanti, A; Nielsen, MA (通讯作者)，Univ Copenhagen, Ctr Med Parasitol, Dept Infect Dis, Copenhagen, Denmark.;Salanti, A; Nielsen, MA (通讯作者)，Copenhagen Univ Hosp, Copenhagen, Denmark.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2023; 42 (1):

Abstract

BackgroundThe malaria protein VAR2CSA binds oncofetal chondroitin sulfate (ofCS), a unique chondroitin sulfate, expressed on almost all mammalian canc......

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