Evidence that methylglyoxal and receptor for advanced glycation end products are implicated in bladder dysfunction of obese diabetic ob/ob mice

Oliveira, AL; Medeiros, ML; Ghezzi, AC; dos Santos, GA; Mello, GC; Monica, FZ; Antunes, E

Antunes, E (通讯作者)，Univ Estadual Campinas, Fac Med Sci, Dept Translat Med, Pharmacol Area, Campinas, Brazil.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (4): F436

Abstract

Glycolytic overload in diabetes causes large accumulation of the highly reactive dicarbonyl compound methylglyoxal (MGO) and overproduction of advance......

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