EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation

Zingg, D; Debbache, J; Pena-Hernandez, R; Antunes, AT; Schaefer, SM; Cheng, PF; Zimmerli, D; Haeusel, J; Calcada, RR; Tuncer, E; Zhang, YD; Bossart, R; Wong, KK; Basler, K; Dummer, R; Santoro, R; Levesque, MP; Sommer, L

Sommer, L (reprint author), Univ Zurich, Inst Anat, Stem Cell Biol, Winterthurerstr 190, CH-8057 Zurich, Switzerland.

CANCER CELL, 2018; 34 (1): 69

Abstract

Human melanomas frequently harbor amplifications of EZH2. However, the contribution of EZH2 to melanoma formation has remained elusive. Taking advanta......

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