Loss of NFE2L3 protects against inflammation-induced colorectal cancer through modulation of the tumor microenvironment

Saliba, J; Coutaud, B; Makhani, K; Roth, NE; Jackson, J; Park, JY; Gagnon, N; Costa, P; Jeyakumar, T; Bury, M; Beauchemin, N; Mann, KK; Blank, V

Blank, V (通讯作者)，Lady Davis Inst Med Res, Montreal, PQ, Canada.;Blank, V (通讯作者)，McGill Univ, Dept Med, Montreal, PQ, Canada.;Blank, V (通讯作者)，McGill Univ, Dept Physiol, Montreal, PQ, Canada.

ONCOGENE, 2022; 41 (11): 1563

Abstract

We investigated the role of the NFE2L3 transcription factor in inflammation-induced colorectal cancer. Our studies revealed that Nfe2l3(-/-) mice exhi......

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