Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-containing pyrazolo[3,4-b]pyridinones as a new series of AMPK alpha 1 beta 1 gamma 1 activators

Xiao, ZH; Peng, YJ; Zheng, BF; Chang, Q; Guo, YT; Chen, Z; Li, QB; Hu, GY

Li, QB; Hu, GY (corresponding author), Cent South Univ, Xiangya Sch Pharmaceut Sci, Dept Med Chem, Changsha 410013, Peoples R China.

ARCHIV DER PHARMAZIE, ; ():

Abstract

Adenosine monophosphate-activated protein kinase (AMPK) plays a key role in maintaining whole-body homeostasis and has been regarded as a therapeutic ......

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