PD-1 siRNA-Encapsulated Solid Lipid Nanoparticles Downregulate PD-1 Expression by Macrophages and Inhibit Tumor Growth: PD-1 siRNA-Encapsulated Solid Lipid Nanoparticles

Hanafy, MS; Hufnagel, S; Trementozzi, AN; Sakran, W; Stachowiak, JC; Koleng, JJ; Cui, ZR

Cui, ZR (corresponding author), Univ Texas Austin, Coll Pharm, Div Mol Pharmaceut & Drug Delivery, Austin, TX 78712 USA.

AAPS PHARMSCITECH, 2021; 22 (2):

Abstract

The present study was designed to test the hypothesis that programmed cell death-1 (PD-1) siRNA can downregulate PD-1 expression in macrophages in cul......

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