Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells

Wu, ZX; Teng, QX; Cai, CY; Wang, JQ; Lei, ZN; Yang, YQ; Fan, YF; Zhang, JY; Li, J; Chen, ZS

Li, J (reprint author), Wuhan Univ, Zhongnan Hosp, Dept Otolaryngol Head & Neck Surg, Wuhan 430071, Hubei, Peoples R China.; Chen, ZS (reprint author), St Johns Univ, Inst Biotechnol, Dept Pharmaceut Sci, Coll Pharm & Hlth Sci, Queens, NY 11439 USA.

BIOCHEMICAL PHARMACOLOGY, 2019; 166 (): 120

Abstract

Overexpression of ABCB1 transporters plays a crucial role in mediating multidrug resistance (MDR). Therefore, it is important to inhibit ABCB1 activit......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索