PKM2 promotes reductive glutamine metabolism

Liu, M; Wang, YY; Ruan, YX; Bai, CS; Qiu, L; Cui, YF; Ying, GG; Li, BH

Li, BH (reprint author), Tianjin Med Univ Canc Inst & Hosp, Natl Clin Res Ctr Canc, Dept Canc Cell Biol, Key Lab Canc Prevent & Therapy, Tianjin, Peoples R China.; Li, BH (reprint author), Tianjins Clin Res Ctr Canc, Tianjin 300060, Peoples R China.

CANCER BIOLOGY & MEDICINE, 2018; 15 (4): 389

Abstract

Objective: Pyruvate kinases M (PKM), including the PKM1 and PKM2 isoforms, are critical factors in glucose metabolism. PKM2 promotes aerobic glycolysi......

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