Metabolic Stability Assessment of Larotrectinib Using Liquid Chromatography Tandem Mass Spectrometry

Attwa, MW; Kadi, AA; Darwish, HW

Darwish, HW (corresponding author), King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia.; Darwish, HW (corresponding author), Cairo Univ, Fac Pharm, Analyt Chem Dept, Cairo 11562, Egypt.

DRUG DESIGN DEVELOPMENT AND THERAPY, 2020; 14 (): 111

Abstract

Introduction: Larotrectinib (VITRAKVI) is an orally potent tropomyosin receptor kinase (Trk) inhibitor that acts by competitive inhibition of all corr......

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